简介：The new age-based MTA cutoff showed better diagnostic accuracy for detecting DAT than previousstandard, the list of practical cut-offs proposed here might be useful in clinical practice.
Scores of MTA correlated to age and Mini-mental state examination score. When used to detect DAT from
NC, the MTA showed highest diagnostic value than other scales, and when the cutoff score of 1.5 of MTA scale, it
obtained an optimal sensitivity (84.5%) and specificity (79.1%) respectively, with a 15.5% of false negative rate.
Cutoff scores and diagnostic values were calculated stratified by age. For the age ranges 50–64, 65–74, 75–84 years,
the following cut-offs of MTA should be used, ≥1.0(sensitivity and specificity were 92.3 and 68.4%), ≥1.5(sensitivity
and specificity were 90.4 and 85.2%), ≥ 2.0(sensitivity and specificity were 70.8 and 82.3%) respectively. All of the
scales showed relatively lower diagnostic values for discriminating aMCI from NC.
